How to Make Beef and Biscuit Casserole

Beef and Biscuit Casserole: A Classic American Comfort Dish

This hearty beef and biscuit casserole brings together all the elements of perfect comfort food — seasoned ground beef, creamy cheese, and a golden biscuit crust that bakes up tender and flavorful. Each layer complements the next, creating a cozy and satisfying meal that’s easy enough for busy weeknights yet special enough for family dinners.

With its savory beef filling, creamy topping, and melted cheese, this casserole offers a perfect balance of texture and taste. It’s rich, homey, and guaranteed to please both kids and adults.

Ingredients

For the Meat Layer

  • 1 pound ground beef
  • 1 packet taco seasoning
  • 1 cup water
  • 1 can (10 oz) diced tomatoes with green chilies, drained
  • ½ cup chopped onion (optional)
  • Salt and black pepper to taste

For the Creamy Layer

  • ½ cup sour cream
  • ½ cup mayonnaise
  • 1 cup shredded cheddar cheese

For the Crust and Topping

  • 1 can (8-count) refrigerated biscuit dough
  • 1 cup shredded cheddar cheese for topping

Instructions

1. Prepare the Base
Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.

2. Cook the Beef Mixture
In a large skillet over medium heat, cook the ground beef until browned. Drain any excess fat. Stir in taco seasoning and water, simmer for a few minutes until the mixture thickens, then add diced tomatoes and onions. Cook for 2–3 minutes, season with salt and pepper, and remove from heat.

3. Create the Biscuit Crust
Press the biscuit dough evenly into the bottom of the baking dish, overlapping slightly to create a solid base.

4. Assemble the Layers
Spread the beef mixture evenly over the biscuit crust. In a separate bowl, mix together the sour cream, mayonnaise, and one cup of cheddar cheese. Spread this creamy mixture over the beef layer, then sprinkle the remaining cheese on top.

5. Bake and Serve
Bake uncovered for 25–30 minutes, or until the cheese is melted and bubbly and the biscuit base is golden brown. Let it rest for 5 minutes before slicing and serving.

Tips and Variations

  • Add Vegetables: Include bell peppers, corn, or black beans for a heartier meal.
  • Add Spice: Mix in diced jalapeños or chili flakes for extra heat.
  • Different Cheese: Try Monterey Jack or pepper jack for a new flavor.
  • Lighter Option: Use ground turkey or chicken and substitute Greek yogurt for sour cream.
  • Make Ahead: Assemble the casserole a day in advance and refrigerate; bake before serving.

Serving Suggestions

Pair this casserole with:

  • A crisp green salad or avocado-tomato salad
  • Steamed vegetables like broccoli or green beans
  • Cornbread, garlic bread, or tortilla chips
  • Fresh fruit or vanilla ice cream for dessert

Frequently Asked Questions (FAQ)

Q1: Can I make this casserole ahead of time?
Yes. You can assemble it up to 24 hours ahead, cover it tightly, and refrigerate. Add 10 extra minutes to the baking time when baking straight from the fridge.

Q2: Can I freeze it?
Absolutely. Freeze either before or after baking in an airtight container for up to 3 months. Thaw overnight in the refrigerator and reheat at 350°F until warmed through.

Q3: Can I make it vegetarian?
Yes. Replace the beef with sautéed mushrooms, black beans, or lentils for a delicious meat-free version.

Q4: How do I keep the biscuit layer from getting soggy?
Avoid over-saturating the layers with sauce and ensure the beef mixture isn’t too watery before assembling.

Q5: What side dishes go best with this casserole?
It pairs perfectly with simple sides like a salad, roasted corn, or refried beans for a Southwestern touch.

Nutrition Facts (Estimated per serving — 6 servings)

Calories: 480
Protein: 27g
Carbohydrates: 22g
Fat: 32g
Saturated Fat: 14g
Cholesterol: 95mg
Sodium: 830mg
Fiber: 2g
Sugars: 3g

Conclusion

This beef and biscuit casserole is everything a comfort dish should be — hearty, creamy, cheesy, and deeply satisfying. It’s quick to prepare, customizable to your taste, and perfect for feeding a crowd or meal prepping for the week. Whether served for a cozy family dinner or a potluck gathering, it always delivers warm, home-cooked goodness in every bite.